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By 2013, health reform regulation will establish uniform requirements for the long-term care (LTC) pharmacy market to dispense shorter cycle medication prescriptions in an attempt to reduce patient waste associated with 30-day cycle fills. There has been much debate in the market of determining these requirements based upon limited information and data. In 2010, a six-month industrial engineering pilot study was conducted in 12 pharmacies across the United States that dispense oral solids in different refill cycles and packaging formats including bingo cards, unit-dose boxes, multi-dose reusable cards, unit-dose reusable cassettes, and unit-dose and multi-dose automation strips. This study measured the average pharmacy’s patient costs including materials, labor, administration, and waste across the different packaging formats.